α-Benzyl-γ-L-glutamyltaurine as a useful intermediate for the synthesis of a brain-peptide, γ-L-glutamyltaurine

Article abstract of DOI:10.1055/s-1992-26105

The synthesis of a neuropeptide, γ-L-glutamyltaurine (3a), was achieved via α-benzyl-γ-L-glutamyltaurine (2a) as a useful intermediate, which was prepared from α-benzyl N-tert-butoxycarbonyl-r-glutamate (1a) and taurine (2-aminoethanesulfonic acid) by active ester method. The preparation of its α-isomer 3b was also described.