Synthetic Communications p. 1179 - 1186 (1992)
Update date:2022-07-30
Topics: Asymmetric synthesis Enantiomer Optically active Organic synthesis Chiral compound S-(+)-2-amino-4-phosphonobutanoic acid Phosphonobutanoic acid
Jiao
Chen
Hu
A novel asymmetric synthetic route to S(+)-2-amino-4-phosphonobutanoic acid through the cyclic condensation of ethyl-4-diethyoxyphosphonyl-2-oxo-butanoate with L-erythro-(+)-1,2-diphenyl-2-hydroxyethylamine, followed by reduction and hydrolysis is describ
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