A novel asymmetric synthesis of S-(+)-2-amino-4-phosphonobutanoic acid

Article abstract of DOI:10.1080/00397919208021103

A novel asymmetric synthetic route to S(+)-2-amino-4-phosphonobutanoic acid through the cyclic condensation of ethyl-4-diethyoxyphosphonyl-2-oxo-butanoate with L-erythro-(+)-1,2-diphenyl-2-hydroxyethylamine, followed by reduction and hydrolysis is describ