Journal of Organic Chemistry p. 1087 - 1094 (1994)
Update date:2022-09-26
Topics:
Arai, Hitoshi
Kasai, Masaji
Synthesis of novel 6-demethyl-6-halomitomycins (3, 4, 6, and 7) and 6-demethyl-6-thiomytomycins (5 and 8) is described from key intermediates, namely, 6-demethyl-7,7-(ethylenedioxy)-6,6-dihalo-6,7-dihydromitosanes (18 and 19) and 6-demethyl-7,7-(ethylenedioxy)-6,7-dihydro-6-thiomitosane (20), respectively.Compounds 18-20 were prepared through a tandem Michael addition and a retro-Mannich reaction sequence (N-halosucinimide or cationic arylsulfenyl species in the presence of Et2NH) on 10.
View MoreBuffett (China) Holding Co.,Ltd
Contact:4006570891
Address:
Longhui qunfeng Chemical Co., Ltd
Contact:86-731-82173407
Address:South-east Industrial Park, Longhui County, Hunan Province, China
Contact:86-574-26865651
Address:529 YuanBaoShan Road, Beilun District
Chongqing Rong＆Quan Pharmaceutical Technology Co. , Ltd.
Contact:86-023-65268721
Address:No. 7, Manshanhong Village, Pingdingshan, Shapingba District, Chongqing Province, China
ZHIJIANG ZENVA SINO COMMERCE AND TRADE CO., LTD.
website:http://www.zenvasino.com
Contact:+86-138-72658998
Address:Shibeishan Road,Zhijiang, Hubei, China
Doi:10.1039/d0ra06876d
(2020)Doi:10.1007/s10562-016-1793-7
(2016)Doi:10.1021/ja400639q
(2013)Doi:10.1021/ma400042u
(2013)Doi:10.1248/cpb.42.2135
(1994)Doi:10.1021/jo400221x
(2013)
