Synthesis and antibacterial activity of C4 substituted monobactams

DOI: 10.1016/0223-5234(92)90101-6

Source and publish data:

European Journal of Medicinal Chemistry p. 131 - 140 (1992)

Update date:2022-09-26

Topics:

Authors:

Arnould Arnould

Boutron Boutron

Pasquet Pasquet

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Article abstract of DOI:10.1016/0223-5234(92)90101-6

The synthesis and antibacterial activity of a series of monobactams having substituents at C4 position is described. An efficient route to versatile intermediates 4a-c from 6-aminopenicillanic acid (6-APA) has been developed. Derivatives 10e, 11, 21 showe

Full text of DOI:10.1016/0223-5234(92)90101-6

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