
European Journal of Medicinal Chemistry p. 131 - 140 (1992)
Update date:2022-09-26
Topics:
Arnould
Boutron
Pasquet
The synthesis and antibacterial activity of a series of monobactams having substituents at C4 position is described. An efficient route to versatile intermediates 4a-c from 6-aminopenicillanic acid (6-APA) has been developed. Derivatives 10e, 11, 21 showe
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