Synthesis of the acridone alkaloids glyfoline and congeners. Structure- activity relationship studies of cytotoxic acridones

DOI: 10.1021/jm00092a022

Source and publish data:

Journal of Medicinal Chemistry p. 2703 - 2710 (1992)

Update date:2022-08-04

Topics:

Authors:

Kohler Kohler

Chou Chou

Moon Woo Chun

Watanabe

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Article abstract of DOI:10.1021/jm00092a022

Glyfoline (4, 1,6-dihydroxy-10-methyl-2,3,4,5-tetramethoxyacridin-9-one) and its congeners were synthesized for evaluation of their cytotoxicity. A detailed structure-activity relationships (SAR) of these acridone derivatives were also studied. To study t

Full text of DOI:10.1021/jm00092a022

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