New optical resolution method based on the formation of a solid solution. Optical resolution of racemic 1-(4-methylthiophenyl)-2-phenylpropan-1-one by co-crystallization with (+)-1-(4-methoxyphenyl)-2-phenylpropan-1-one

Article abstract of DOI:10.1016/S0957-4166(00)80275-X

Crystallization of ketone S-(+)-1 in the presence of a small amount of it sulfur analogue (±)-2 afforded a solid solution containing 8% of S-(+)-2; the latter was isolated in enantiomerically pure form by column chromatography. This simple optical resolut