Synthesis of some 4-chloro-5-cyano-2-dialkylamino-6H-1,3-oxazin-6-ones and their reactions with trialkyl phosphites to give dialkyl (5-cyano-2-dialkylamino-6-oxo-6H-1,3-oxazin-4-yl)phosphonates

Article abstract of DOI:10.1055/s-1992-26129

The reaction of the salts of alkyl dicyanoacetates and N-(dichloromethylene)dialkylammonium chlorides in chloroform leads to 4-chloro-5-cyano-2-dialkylamino-6H-1,3-oxazin-6-ones. The chloro atom of these compounds can be easily substituted in a Michaelis-