Chemical modification of the sugar part of methyl acarviosin: Synthesis and inhibitory activities of nine analogues

Article abstract of DOI:10.1016/0008-6215(92)84132-C

Nine analogues of methyl acarviosin (1), the core structure of acarbose and its homologues, the 6-hydroxy-(2), 6-azido-(3), 6-amino-(4), 6-acctamido-(5), 6-methoxy-(6), 6-hydroxy-2-O-methyl-(8), and 6-hydroxy-3-O-methyl derivatives (9), including the 5-me