Non-Prostanoid Thromboxane A2 Receptor Antagonists with a Dibenzoxepin Ring System. 2.

DOI: 10.1021/jm00096a017

Source and publish data:

Journal of Medicinal Chemistry p. 3402 - 3413 (1992)

Update date:2022-09-26

Topics:

Authors:

Ohshima, Etsuo

Takami, Hitoshi

Sato, Hideyuki

Mohri, Shinichiro

Obase, Hiroyuki

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00096a017

A series of 11-<2-(1-benzimidazoyl)ethylidene>-6,11-dihydrodibenzoxepin-2-carboxylic acid derivatives and related compounds were synthesized and found to be potent TXA₂/PGH₂ receptor antagonists.Each compound synthesized was tes

Full text of DOI:10.1021/jm00096a017

Products guided by the article

Product name:2-({11-[2-(5,6-Dimethyl-benzoimidazol-1-yl)-eth-(E)-ylidene]-6,11-dihydro-dibenzo[b,e]oxepine-2-carbonyl}-amino)-benzoic acid

Cas No:142535-64-6

R&D Labs maybe for 142535-64-6

WEIFANG RICHEM INTERNATIONAL LTD

Contact:86-536-2222176

Address:weifang,shandong
Suzhou Lixin Pharmaceutical Co., Ltd.

Contact:86-512-88169812

Address:21 Tangxi Road, Suzhou New District, Suzhou 215151
Dongtai Xinyuan Chemical Co., Ltd.

Contact:+86-21-56733000

Address:404F, 99Nong No.117 Zhongtan Rd. Shanghai
Henan Harvest Chem Co., Ltd

Contact:+86-371-86058576

Address:NO.32, Jingsan Road, Zhengzhou, China
Shaanxi King Stone Enterprise Company Limited

Contact:86-29-88353805,13609285751

Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China

Relevant to this article

Syntheses, structure diversity and properties of complexes with 4-acyl pyrazolone salicylidene hydrazide derivatives

Doi:10.1039/c2dt32641h
(2013)
A benzimidazole-based ratiometric fluorescent sensor for Cr³⁺ and Fe³⁺ in aqueous solution

Doi:10.1016/j.dyepig.2013.02.005
(2013)
Improvement of σ₁ receptor affinity by late-stage C-H-bond arylation of spirocyclic lactones

Doi:10.1016/j.bmc.2013.01.038
(2013)
Design, synthesis and in vitro and in vivo antitumor activities of novel bivalent β-carbolines

Doi:10.1016/j.ejmech.2012.11.033
(2013)
Effect of 1-Substitution on Tetrahydroisoquinolines as Selective Antagonists for the Orexin-1 Receptor

Doi:10.1021/cn500330v
(2015)
Dual spectroscopic responses of pyridinium hemicyanine dyes to anions

Doi:10.1002/cjoc.201180343
(2011)

Article Doi