Non-Prostanoid Thromboxane A2 Receptor Antagonists with a Dibenzoxepin Ring System. 2.

DOI: 10.1021/jm00096a017

Source and publish data:

Journal of Medicinal Chemistry p. 3402 - 3413 (1992)

Update date:2022-09-26

Topics:

Authors:

Ohshima, Etsuo

Takami, Hitoshi

Sato, Hideyuki

Mohri, Shinichiro

Obase, Hiroyuki

et al. et al.

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Article abstract of DOI:10.1021/jm00096a017

A series of 11-<2-(1-benzimidazoyl)ethylidene>-6,11-dihydrodibenzoxepin-2-carboxylic acid derivatives and related compounds were synthesized and found to be potent TXA₂/PGH₂ receptor antagonists.Each compound synthesized was tes

Full text of DOI:10.1021/jm00096a017

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Product name:2-({11-[2-(5,6-Dimethyl-benzoimidazol-1-yl)-eth-(E)-ylidene]-6,11-dihydro-dibenzo[b,e]oxepine-2-carbonyl}-amino)-benzoic acid

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