Synthesis and biological evaluation of nucleosides containing 8-amino- imidazo[1,2-a]pyrazine as an isosteric replacement for adenine [1]

DOI: 10.1002/jhet.5570300508

Source and publish data:

Journal of Heterocyclic Chemistry p. 1213 - 1220 (1993)

Update date:2022-08-04

Topics:

Authors:

MacCoss MacCoss

Meurer Meurer

Hoogsteen

Springer

Koo Koo

Peterson

Tolman Tolman

Emini Emini

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Article abstract of DOI:10.1002/jhet.5570300508

A number of novel C-nucleosides related to purine derivatives are described in which the purine moiety has been replaced by the isosteric heterocycle, 8-aminoimidazo[1,2-a]pyrazine. The nucleosides prepared include the ribo, 3'-deoxy,2',3'-dideoxy, and 2'

Full text of DOI:10.1002/jhet.5570300508

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