Synthesis and biological evaluation of nucleosides containing 8-amino- imidazo[1,2-a]pyrazine as an isosteric replacement for adenine [1]

DOI: 10.1002/jhet.5570300508

Source and publish data:

Journal of Heterocyclic Chemistry p. 1213 - 1220 (1993)

Update date:2022-08-04

Topics:

Authors:

MacCoss MacCoss

Meurer Meurer

Hoogsteen

Springer

Koo Koo

Peterson

Tolman Tolman

Emini Emini

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/jhet.5570300508

A number of novel C-nucleosides related to purine derivatives are described in which the purine moiety has been replaced by the isosteric heterocycle, 8-aminoimidazo[1,2-a]pyrazine. The nucleosides prepared include the ribo, 3'-deoxy,2',3'-dideoxy, and 2'

Full text of DOI:10.1002/jhet.5570300508

Products guided by the article

Product name:3,6-anhydro-1-deoxy-1-(3-chloropyrazin-2-ylamino)-4,5-O-isopropylidene-7-O-trityl-D-allo-hept-2-ulositol

Cas No:142588-94-1

R&D Labs maybe for 142588-94-1

Beijing Green Guardee Technology CO,.LTD

Contact:+86-10-69706062

Address:F2 BLdj,5 No.37 Chaoqian Road
Tianjin Pharmacn Medical Technology Co.,Ltd.

Contact:86-22-60122566ext.866(English),23359620

Address:Green Industrial Base, 6 Haitaifazhan Sixth Rd., Huayuan Industrial Area, Tianjin, 300384, China
Liaoyang hengye Chemical Co., Ltd.

Contact:86-419-5850866

Address:North Old Xiaoxiao Road,Yantai District, Dengta, Liaoyang, Liaoning, China
RongCheng K&S Chemical Co.,Ltd

Contact:0631-7336369

Address:rongcheng ,shandong province china
TIANJIN ZHONGXIN CHEMTECH CO.,LTD.

Contact:86-022-66880623

Address:FINANCIAL STREET WEST BLK 7, #308, NO.52 XINCHENG WEST ROAD, TEDA, TIANJIN, P.R.CHINA

Relevant to this article

Stereoselective C-glycoside formation by a rhodium(I)-catalyzed 1,4-addition of arylboronic acids to acetylated enones derived from glycals

Doi:10.1021/ol016245d
(2001)
Iodine-catalyzed disproportionation of aryl-substituted ethers under solvent-free reaction conditions

Doi:10.1039/c3ob27267b
(2013)
Development of quinoline-based disruptors of biofilm formation against Vibrio cholerae

Doi:10.1021/ol400150z
(2013)
Stereoselective Synthesis of 2-(2-Aminoalkyl)- and 1,3-Disubstituted Tetrahydro-1H-pyrido[4,3-b]- Benzofuran and Indole Derivatives

Doi:10.1021/acs.joc.6b01047
(2016)
Regioselective ring-emitting esterification on azacyclohexane quaternary salts: A DFT and synthetic study for covalent fixation of electrostatic polymer self-assemblies

Doi:10.1021/jo400058f
(2013)
Rearrangements of 4-Alkynyl-, 4-Alkenyl-, and 4-Alkyl-4-hydroxy-3-methylenecyclobutenes

Doi:10.1021/jo00044a004
(1992)

Article Doi