Preparation of phosphonium salt from (S)-trifluoropropene oxide and wittig type reactions

Article abstract of DOI:10.1016/S0040-4039(00)92255-X

(-S)-Trifluoropropene oxide was reacted with triphenylphosphine in the presence of trifluoroacetic acid to afford the corresponding β-hydroxyalkyl phosphonium salt. Wittig type reaction of aldehydes with the salt under basic condition readily occurred to