Synthesis and anti-human immunodeficiency virus type 1 (HIV-1) activity of 3-substituted derivatives of 3'-azido-3'-deoxythymidine (AZT), and inhibition of HIV-1 reverse transcriptase by their 5'-triphosphates

DOI: 10.1248/cpb.40.920

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 920 - 924 (1992)

Update date:2022-09-26

Topics:

Authors:

Kitade Kitade

Suzuki Suzuki

Hirota Hirota

Maki Maki

Nakane Nakane

Ono Ono

Baba Baba

Shigeta Shigeta

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.40.920

Various 3-substituted 3'-azido-3'-deoxythymidine analogs (2a-i) were prepared by the reaction of 3'azido-3'-deoxythymidine (1), AZT with N,N-dimethylformamide dialkylacetal or alkyl bromide in the presence of base and their activities against human-immuno

Full text of DOI:10.1248/cpb.40.920

NII-Electronic Library Service

Products guided by the article

Product name:N(3)-methyl-3'-azido-3'-deoxythymidine 5'-triphosphate

Cas No:142644-39-1

R&D Labs maybe for 142644-39-1

Nanjing Chemipioneer Pharma&Tech Co.,Ltd

website:http://www.chemipioneer.com.cn

Contact:+86-25-52685700

Address:Room 305，A Block，Biological-Medicine Building，Business Start-up Center，Xin-ke 1st Road, High-tech development zone，Nanjing city，Jiangsu Province, China
Jingzhou TianHe Sci&Tech Chemical Co., Ltd.

Contact:86-716-8331612

Address:Jiangjin Road, #18, High-grade technology industries development district, Jingzhou city, Hubei province
Tianjin Chemsyntech Chemical Co., Ltd

Contact:+86-22-60872258

Address:Haitai green industry base in Tianjin, K1,5-601
Jiangsu Jiuri Chemical Co.,Ltd.

Contact:+86-519-82118868

Address:Tianwang Town, Jurong City, Jiangsu Province, China
Dayang Chem (Hangzhou) Co.,Ltd.

website:http://www.dycnchem.com

Contact:+86-571-88938639

Address:9/F, Unit 2 Changdi Torch Building, 259# WenSan Road, Xihu District, Hangzhou City 310012, P.R.China

Relevant to this article

Exploration of Aryllithium-Derived Copper Reagents for Quaternary-Stereogenic-Center-Forming Allylic Substitution of γ,γ-Disubstituted Secondary Allylic Picolinates

Doi:10.1055/s-0035-1560907
(2016)
A Unified Approach for the Total Synthesis of cyclo-Archaeol, iso-Caldarchaeol, Caldarchaeol, and Mycoketide

Doi:10.1002/anie.202104759
(2021)
Formal synthesis of (-)-oseltamivir phosphate

Doi:10.1055/s-0032-1317948
(2013)
A highly selective fluorescent probe for Al³⁺ based on 4-aminoantipyrine

Doi:10.1016/j.saa.2012.12.084
(2013)
Dimerized linear mimics of a natural cyclopeptide (TMC-95A) are potent noncovalent inhibitors of the eukaryotic 20S proteasome

Doi:10.1021/jm4002007
(2013)
Doi:10.1021/ja00424a066
(1976)

Article Doi