Tetrahedron Letters p. 2629 - 2632 (1992)
Update date:2022-08-04
Topics:
Hsiao, Chi-Nung
Kolasa, Teodozyj
Coupling and intramolecular Wittig reaction of N-benzyloxy-D-alanine anhydride (13) and (2-Mercaptophenyl)methyltriphenylphosphonium bromide (3) were used as key steps to prepare (+)-enantiomer of zileuton (1), a potent and selective inhibitor of 5-lipoxygenase.
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Doi:10.1039/c3ra44726j
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(2012)
