Journal of Medicinal Chemistry p. 2772 - 2781 (1992)
Update date:2022-07-29
Topics:
Ashton, Wallace T.
Cantone, Christine L.
Tolman, Richard L.
Greenlee, William J.
Lynch, Robert J.
et al.
New transition-state analogues bearing C-termini derived from α-mercaptoalkanoic acids, esters, and amides were prepared and evaluated as inhibitors of human renin.Addition of α-mercaptoalkanoate esters to a chiral Boc-amino epoxide intermediate led ultim
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