Journal of the Chemical Society. Perkin transactions I p. 2993 - 3000 (1994)
Update date:2022-09-26
Topics:
Ishihara, Yuji
Tanaka, Toshimasa
Miwatashi, Seiji
Fujishima, Akira
Goto, Giichi
It is revealed that NH-protected 2,3,4,5-tetrahydro-1H-2-benzazepine 4 is acylated on C-8 with greater than 95percent regioselectivity.This regioselectivity has been applied to the synthesis of 3-(1-benzylpiperidin-4-yl)-1-(2,3,4,5-tetrahydro-1H-2-benzaze
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