Journal of Medicinal Chemistry p. 3463 - 3469 (1992)
Update date:2022-07-30
Topics:
Bulusu, Murty A. R. C.
Waldstaetten, Peter
Hildebrandt, Johannes
Schuetze, Eberhard
Schulz, Gerhard
The synthesis of a series of novel acyclic analogues of lipid A, the lipophilic terminal of lipopolysaccharide (LPS), is reported.In these compounds, the reducing glucose unit of lipid A has been replaced by an acyclic analogue unit (abbreviated as AAU) c
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