A facile and convenient synthetic method for N-β-trifluoroacetylvinyl amino acid esters, α-aminoacetophenones and aminoacetonitriles as potentially useful precursors of fluorine-containing pyrroles

DOI: 10.1055/s-1992-26155

Source and publish data:

Synthesis p. 533 - 535 (1992)

Update date:2022-08-05

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Authors:

Okada Okada

Masuda Masuda

Hojo Hojo

Inoue Inoue

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Article abstract of DOI:10.1055/s-1992-26155

N-(4,4,4-Trifluoro-3-oxo-1-butenyl) amino acid esters, α-aminoacetophenones and aminoacetonitriles 3 and 4 are easily obtained in excellent yields by O-N exchange reaction of 4-alkoxy-1,1,1-trifluoro-3-alken-2-ones 1 and 2 with some amino acid esters, α-a

Full text of DOI:10.1055/s-1992-26155

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