Endothelium dependent and independent mechanisms of vasorelaxant activity of synthesized 2,5-disubstituted-1,3,4-oxadiazole derivatives in rat thoracic aorta-ex vivo and molecular docking studies

DOI: 10.2174/1570180812666150907203634

Source and publish data:

Letters in drug design and discovery p. 441 - 450 (2016)

Update date:2022-09-26

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Authors:

Attari, Zenab

Mudgal, Jayesh

Nayak, Pawan G.

Krishnadas, Nandakumar

Rajappan, Revathi

Gopalan Kutty

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Article abstract of DOI:10.2174/1570180812666150907203634

Background: Vasoconstriction is a major pathological feature of cardiovascular diseases involving endothelium dependent and independent mechanisms. Oxadiazole moiety appeared to be effective in various pathologies. Objective: The aim of the study was to s

Full text of DOI:10.2174/1570180812666150907203634

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Product name:4-[3-acetyl-5-(pyridine-4-yl)-2,3-dihydro-1,3,4-oxadiazol-2-yl]phenyl acetate

Cas No:1430799-99-7

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