Chiral 2-Cyanocinnamates in Conjugate Addition Asymmetric Enolate Trapping Reactions

DOI: 10.1246/bcsj.65.1657

Source and publish data:

Bulletin of the Chemical Society of Japan p. 1657 - 1661 (1992)

Update date:2022-08-03

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Authors:

Cativiela, Carlos

Diaz-de-Villegas, Maria Dolores

Galvez, Jose Antonio

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Article abstract of DOI:10.1246/bcsj.65.1657

Chiral 2-cyannocinnamates react with L-selectride<*> to give an intermediate enolate which can be stereoselectively trapped with different halides to afford α-substituted phenylalanine precursors with excellent chemical yields and good diastereomeric excess.

Full text of DOI:10.1246/bcsj.65.1657

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