An unexpected reaction in the lactamisation of 13-azido-13-deoxy-(9S)-9-dihydroerythronolide A seco-acid derivatives

DOI: 10.1016/S0040-4039(00)92532-2

Source and publish data:

Tetrahedron Letters p. 3669 - 3672 (1992)

Update date:2022-08-04

Topics:

Authors:

Bartra Bartra

Urpi Urpi

Vilarrasa

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Article abstract of DOI:10.1016/S0040-4039(00)92532-2

By reduction of the title compounds (azido acid derivatives 2) and cyclisation in situ, either the desired lactam 3 or unexpected acyl triazene 4 can be predominantly obtained, depending on the reaction conditions.

Full text of DOI:10.1016/S0040-4039(00)92532-2

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