An unexpected reaction in the lactamisation of 13-azido-13-deoxy-(9S)-9-dihydroerythronolide A seco-acid derivatives

DOI: 10.1016/S0040-4039(00)92532-2

Source and publish data:

Tetrahedron Letters p. 3669 - 3672 (1992)

Update date:2022-08-04

Topics:

Authors:

Bartra Bartra

Urpi Urpi

Vilarrasa

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)92532-2

By reduction of the title compounds (azido acid derivatives 2) and cyclisation in situ, either the desired lactam 3 or unexpected acyl triazene 4 can be predominantly obtained, depending on the reaction conditions.

Full text of DOI:10.1016/S0040-4039(00)92532-2

Products guided by the article

Product name:(Z)-(1S,2R,4R,5R,7R,9S,10R,15R,16R,17R,19R,21S,22S)-15-Ethyl-4,16-dihydroxy-2,4,10,16,21,22-hexamethyl-7,19-diphenyl-6,8,18,20-tetraoxa-12,13,14-triaza-tricyclo[15.3.1.1^5,9]docos-13-en-11-one

Cas No:143140-25-4

R&D Labs maybe for 143140-25-4

Guangzhou Flower's Song Fine Chemical CO,. Ltd

Contact:+86-20-87475199

Address:No.12, Fenghuang 3 Road, Jiulong Industrial Park, Luogang District, Guangzhou. China
Jinan Trio PharmaTech Co., Ltd

Contact:86-531-88811783；+(0)13153010282

Address:2766 Yingxiu Road, Jinan High-Tech Zone, China
Chengdu Aslee Biopharmaceuticals, Inc

Contact:18608018419

Address:Chengdu Aslee Biopharmaceuticals, Inc
Hebei Tianxiang Biological & Pharmaceutical Co., Ltd

Contact:86-0312-6615158

Address:No 42 fazhan street qingyuan county
Acorn PharmaTech Co., Ltd

Contact:86-25-58619180

Address:Nanjing High-Tech Zone 10 Xinghuo Road Pukou District Nanjing, Jiangsu 210061 The People's Republic of China

Relevant to this article

Structure-activity studies on the side chain of a simplified analog of aplysiatoxin (aplog-1) with anti-proliferative activity

Doi:10.1016/j.bmc.2013.03.013
(2013)
Tuning of tetrathiafulvalene properties: Versatile synthesis of N-arylated monopyrrolotetrathiafulvalenes via Ullmann-type coupling reactions

Doi:10.3762/bjoc.11.96
(2015)
Potent proteasome inhibitors derived from the unnatural cis-cyclopropane isomer of belactosin a: Synthesis, biological activity, and mode of action

Doi:10.1021/jm4002296
(2013)
Organocatalytic oxidation of aldehydes to mixed anhydrides

Doi:10.1039/c2cc35220f
(2013)
Ru(II)-arene complexes with N-substituted 3,4-dihydroquinazoline ligands and catalytic activity for transfer hydrogenation reaction

Doi:10.1016/j.ica.2013.02.005
(2013)
Structure-activity relationship of cytochrome bc1 reductase inhibitor broad spectrum antifungal ilicicolin H

Doi:10.1016/j.bmcl.2013.03.023
(2013)

Article Doi