Journal of Organic Chemistry p. 5700 - 5707 (1992)
Update date:2022-09-26
Topics:
Hoffman, Ribert V.
Nayyar, Naresh K.
Chen, Wenting
Treatment of a series of hydroxamic acids 2 with mesyl chloride in the presence of 2 equiv of triethylamine at 0 deg C gives 2-chloroamides 3 in good yields.Use of a single equivalent of triethylamine gives the N-(mesyloxy)amides 1, which are versatile sy
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