Tetrahedron Letters p. 3607 - 3610 (1992)
Update date:2022-08-05
Topics:
Dehmlow, Henrietta
Mulzer, Johann
Seilz, Carsten
Strecker, Achim R.
Kohlmann, Andreas
Benzyl ethers with SN2 active sites in γ-position undergo spontaneous regio- and stereocontrolled tetrahydrofuran cyclization with concomitant debenzylation even under mildly acidic or neutral conditions. Keywords: tetrahydrofuran; neighboring group participation of benzyl ethers; Mitsunobu conditions; small rings; mesylates.
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