Synthesis of Photoactive DNA: Incorporation of 8-Bromo-2'-Deoxyadenosine into Synthetic Oligodeoxynucleotides

DOI: 10.1016/S0040-4039(00)74234-1

Source and publish data:

Tetrahedron Letters p. 4265 - 4268 (1992)

Update date:2022-08-02

Topics:

Authors:

Liu, Jia

Verdine, Gregory L.

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Article abstract of DOI:10.1016/S0040-4039(00)74234-1

8-Bromo-N⁶-phenoxyacetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite was synthesized and used to introduce 8-bromo-2'-deoxyadenosine (8-Br-dA) into oligodeoxynucleotides by means of automated

Full text of DOI:10.1016/S0040-4039(00)74234-1

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