Synthesis of Spiroimidazolidin-2-ones via Intramolecular N-Carbamoyliminium Ion Cyclization Reaction

Article abstract of DOI:10.1021/jo00211a020

The use of N-carbamoyliminium ion initiated reactions for the generation of spiroimidazolidin-2-ones has been successfully exploited.Treatment of hydantoins with saturated alkyllithium and alkylmagnesium reagents gave the corresponding 4-hydroxyimidazolid