Titanium tetrachloride-mediated enantioselective synthesis of trans β-lactones

DOI: 10.1016/0040-4020(92)80006-2

Source and publish data:

Tetrahedron p. 5557 - 5564 (1992)

Update date:2022-08-05

Topics:

Authors:

Cardani, Silvia

De Toma, Carlo

Gennari, Cesare

Scolastico, Carlo

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Article abstract of DOI:10.1016/0040-4020(92)80006-2

Pharmacologically interesting trans β-lactones 11 and 16 were synthesized using a titanium tetrachloride-mediated enantioselective aldol reaction as the key synthetic step (see Scheme 2).

Full text of DOI:10.1016/0040-4020(92)80006-2

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