Palladium-catalyzed oxidative cross-coupling between heterocycles and terminal alkynes with low catalyst loading

DOI: 10.1002/anie.201210013

Source and publish data:

Angewandte Chemie - International Edition p. 3630 - 3633 (2013)

Update date:2022-08-03

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Authors:

Jie, Xiaoming

Shang, Yaping

Hu, Peng

Su, Weiping

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Article abstract of DOI:10.1002/anie.201210013

Direct: With [Pd₂(dba)₃] as a catalyst, the direct alkynylation of thiophenes bearing a variety of substituents has been accomplished by using terminal alkynes as alkynylating reagents. This protocol is also applicable to other electron-rich aromatic heterocycles. dba=dibenzylidenacetone. Copyright

Full text of DOI:10.1002/anie.201210013

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