An Asymmetric Route to Enantiomerically Pure 1,2,3-Trisubstituted Cyclopropanes

DOI: 10.1021/jo00049a038

Source and publish data:

Journal of Organic Chemistry p. 6265 - 6270 (1992)

Update date:2022-08-04

Topics: Asymmetric synthesis Enantiomerically pure Reaction Conditions Chiral Auxiliary 1,2,3-Trisubstituted Cyclopropanes

Authors:

Romo, Daniel

Meyers, A. I.

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Article abstract of DOI:10.1021/jo00049a038

Cycloadditions of various sulfur ylides to the chiral unsaturated lactams 1a, 1b led to cyclopropanated products containing a monosubstituted appendage.The stereochemical outcome is such that all the products are mainly (or exclusively) the kinetically co

Full text of DOI:10.1021/jo00049a038

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