
Tetrahedron Letters p. 4747 - 4750 (1992)
Update date:2022-08-04
Topics:
Hernandez
Afonso
Gonzalez
Galindo
Pathways to synthesize germacranolides with ether bridges between C1 and C5 or C3 and C10 were described. A joint precursor was prepared using a readily available and inexpensive compound as starting material. The key step in the preparation of dihydropyranone-germacranolides proved to be a one-pot procedure involving several transformation, induced by the iodotrimethylsilane/acetonitrile system.
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Doi:10.1021/jo400342y
(2013)Doi:10.1016/j.tet.2013.03.052
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(1992)Doi:10.1021/ol400845c
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