Synthesis and structural evaluations of thiazolo[3,2-a]pyrimidine derivatives

Article abstract of DOI:10.1002/ardp.19923250809

2-Thioxo-1,2,3,4-tetrahydropyrimidine derivatives 1 were reacted with phenacyl bromide in glacial acetic acid to obtain thiazolo[3,2-a]pyrimidine derivatives. UV-, IR-, and ¹H-NMR spectra and elementary analysis data confirm structures 3. ¹H-{¹H}-NOE techniques showed that the isolated products are H-5 isomers.