Stereochemistry in Carbenoid Formation by Bromine/Lithium and Bromine/Zinc Exchange Reactions of 1,1-Dibromoalkenes: Higher Reactivity of the Sterically More Hindered Bromine Atom

DOI: 10.1021/jo00048a002

Source and publish data:

Journal of Organic Chemistry p. 5805 - 5807 (1992)

Update date:2022-08-04

Topics:

Authors:

Harada, Toshiro

Katsuhira, Takeshi

Oku, Akira

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00048a002

Both lithium and zincate carbenoids (R¹(R²)C=C(Br)M; M = Li and Zn(Bu)2Li) generated by the halogen/metal exchange reaction of 1,1-dibromoalkene 1 with BuLi and (Bu)3ZnLi, respectively, are configurationally stable at low temperature

Full text of DOI:10.1021/jo00048a002

Products guided by the article

Product name:Benzene, [2-bromo-2-chloro-1-(methoxymethyl)ethenyl]-, (E)-

Cas No:144108-91-8

R&D Labs maybe for 144108-91-8

Shanghai FWD Chemicals ltd

website:http://www.fwdchem.com

Contact:86-21-54450828

Address:Room 802,Lotus Tower ,159 Tianzhou Road,Xuhui District,Shanghai
Onlychem (Jinan)Biotech Co.,Ltd

Contact:86-531-83175885

Address:No. 44, Honglou South Road, Jinan,China
lianyungang jinkang pharmaceutical technology co., ltd.

Contact:008651885445517

Address:Jinshan industrial park, Ganyu county, Lianyungang, Jiangsu Province, 222115, China
wuxi huabin bio-tech Co.,Ltd(expird)

Contact:86-0510-85133006

Address:hubin road NO157
Hangzhou TJM Chemical Trade Co., Ltd

Contact:86-571-88223276 86-13388481653

Address:2221#,Boyuexuan,1860# Binsheng Road,Binjiang District, Hangzhou CityZhejiang Province, 310051, P. R. China

Relevant to this article

Synthesis of medium-sized lactones by copper(I) catalyzed atom transfer cyclization

Doi:10.1016/S0040-4039(00)61212-1
(1992)
3-Arylcoumarins as highly potent and selective monoamine oxidase B inhibitors: Which chemical features matter?

Doi:10.1016/j.bioorg.2020.103964
(2020)
Synthesis, structures, and optical properties of aza[4]helicenes

Doi:10.1002/ejoc.201300002
(2013)
Bifunctional cinchona alkaloid-squaramide-catalyzed highly enantioselective aza-Michael addition of indolines to α,β-unsaturated ketones

Doi:10.1016/j.tetlet.2013.04.080
(2013)
Concise solid-phase synthesis of inverse poly(amidoamine) dendrons using AB₂ building blocks

Doi:10.1039/c3cc40661j
(2013)
Synthesis and anticancer activity of novel spiro-isoxazoline and spiro-isoxazolidine derivatives of α-santonin

Doi:10.1016/j.ejmech.2013.01.003
(2013)

Article Doi