Synthesis of medium-sized lactones by copper(I) catalyzed atom transfer cyclization

Article abstract of DOI:10.1016/S0040-4039(00)61212-1

Several ω-alkenyl dichloroacetates cyclize in moderate to excellent yields to 3,5-dichloro-oxocon-2-ones (8-membered ring lactones) when heated in benzene at 80-180°C in the presence of a catalytic amount of the cuprous chloride 2,2′-bipyridine complex.