Inhibitors of Acyl-CoA:Cholesterol Acyltransferase. 1. Synthesis and Hypocholesterolemic Activity of Dibenzoxepin-11-carboxanilides

DOI: 10.1021/jm00032a014

Source and publish data:

Journal of Medicinal Chemistry p. 804 - 810 (1994)

Update date:2022-07-29

Topics:

Authors:

Kumazawa, Toshiaki

Yanase, Masashi

Harakawa, Hiroyuki

Obase, Hiroyuki

Shirakura, Shiro

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00032a014

A series of N-phenyl-6,11-dihydrodibenzoxepin-11-carboxamides and related derivatives were prepared on the basis of structures of the reported inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT).These compounds were tested for their ability to

Full text of DOI:10.1021/jm00032a014

Products guided by the article

Product name:N-(2,6-Dichlorophenyl)-6,11-dihydro-2-methyldibenz[b,e]-oxepin-11-carboxamide

Cas No:144169-98-2

R&D Labs maybe for 144169-98-2

HangZhou HuaYe Chemical Technology Co.,Ltd

Contact:+86-13505815007

Address:hangzhou
TIANJIN NORTH JINHENG CHEMICAL PLANT.

Contact:0086-22-59952083

Address:DongShigu Country In JiXian TianJin China
Geen Chemical Technology Co., Ltd

Contact:86-769-21660847

Address:1408, Yingfeng Commercial Center, Nancheng District
Beijing Mashi Fine Chemical Co.,Ltd.

Contact:+86-10-61271592

Address:Room 506, Section B, Kaichi Mansion, Industrial Development
Zhengzhou Yuanli Biological Technology Co., Ltd.

Contact:+86-371-67897870/67897895

Address:No. 38, Qingyang Street, Zhengzhou, Henan, China

Relevant to this article

Unexpected heteroatom-assisted C-4 alkylation of a 1,3-dioxolane

Doi:10.1016/S0040-4039(00)61316-3
(1992)
Doi:10.1021/ja01144a029
(1952)
A green approach for highly regioselective syntheses of furo[3,2-h]quinolines in aqueous medium

Doi:10.1016/j.tetlet.2013.05.038
(2013)
Crystal structures and antibacterial activity of hydrazone derivatives from 1H-indol-3-acetohydrazide

Doi:10.1134/S0022476613010216
(2013)
Discovery of N-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1 H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain

Doi:10.1021/acs.jmedchem.0c00628
(2020)
C_(sp3)-H functionalization of methyl azaarenes: a calcium-catalyzed facile synthesis of (E)-2-styryl azaarenes and 2-aryl-1,3-bisazaarenes

Doi:10.1016/j.tetlet.2015.09.035
(2015)

Article Doi