Inhibitors of Acyl-CoA:Cholesterol Acyltransferase. 1. Synthesis and Hypocholesterolemic Activity of Dibenzoxepin-11-carboxanilides

DOI: 10.1021/jm00032a014

Source and publish data:

Journal of Medicinal Chemistry p. 804 - 810 (1994)

Update date:2022-07-29

Topics:

Authors:

Kumazawa, Toshiaki

Yanase, Masashi

Harakawa, Hiroyuki

Obase, Hiroyuki

Shirakura, Shiro

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00032a014

A series of N-phenyl-6,11-dihydrodibenzoxepin-11-carboxamides and related derivatives were prepared on the basis of structures of the reported inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT).These compounds were tested for their ability to

Full text of DOI:10.1021/jm00032a014

Products guided by the article

Product name:N-(2,6-Dichlorophenyl)-6,11-dihydro-2-methyldibenz[b,e]-oxepin-11-carboxamide

Cas No:144169-98-2

R&D Labs maybe for 144169-98-2

Quzhou Ruiyuan chemical Co., Ltd

Contact:+86-570-3039321/3039361/3039308

Address:18# Huayang Road,Quzhou High-tech Industrial Park, Zhejiang China.
Taizhou Elitechemie MediPharma Technology Co.,Ltd.

Contact:+86-523-86810021

Address:Building G14,NO.1 Avenue,China Medical City, Taizhou, Jiangsu,China
SEA BRGIHT INDUSTRY CO.,LIMITED

Contact:0086 755 8622 3990

Address:Rm 17B3,GuangCaiXinTianDi Bldg,GuiMiao Rd,NanShan District,Shenzhen,China
XI'AN CHUKANG BIOTECHNOLOGY CO.,LTD

Contact:29-63685658 63685359

Address:Room 3-1202,Building 1,Oriental oasis,East of Xianning Road,Xi'an,Shaanxi 710043 P.R.China
Xian Lyphar Biotech Co., Ltd.

Contact:0086-29-89196322

Address:North of the Fifth Keji Road, Hi-Tech Industrial Zone, Xi'an City, Shaanxi Province, China

Relevant to this article

Unexpected heteroatom-assisted C-4 alkylation of a 1,3-dioxolane

Doi:10.1016/S0040-4039(00)61316-3
(1992)
Doi:10.1021/ja01144a029
(1952)
A green approach for highly regioselective syntheses of furo[3,2-h]quinolines in aqueous medium

Doi:10.1016/j.tetlet.2013.05.038
(2013)
Crystal structures and antibacterial activity of hydrazone derivatives from 1H-indol-3-acetohydrazide

Doi:10.1134/S0022476613010216
(2013)
Discovery of N-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1 H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain

Doi:10.1021/acs.jmedchem.0c00628
(2020)
C_(sp3)-H functionalization of methyl azaarenes: a calcium-catalyzed facile synthesis of (E)-2-styryl azaarenes and 2-aryl-1,3-bisazaarenes

Doi:10.1016/j.tetlet.2015.09.035
(2015)

Article Doi