Unexpected heteroatom-assisted C-4 alkylation of a 1,3-dioxolane

DOI: 10.1016/S0040-4039(00)61316-3

Source and publish data:

Tetrahedron Letters p. 4575 - 4578 (1992)

Update date:2022-07-29

Topics:

Authors:

Marot Marot

Philipp Philipp

Rollin Rollin

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)61316-3

The reaction of a number of organomagnesium halides with a 4-(2-pyridyl)thiomethyl-1,3-dioxolane 1 mainly afforded C-branched pyridylthiopropanols 2. These versatile synthons resulted from an atypical combined aza-/thia-assisted C-4 alkylation of the cyclic ketal system.

Full text of DOI:10.1016/S0040-4039(00)61316-3

Products guided by the article

Product name:Benzeneethanol, b-[(2-pyridinylthio)methyl]-

Cas No:144366-00-7

R&D Labs maybe for 144366-00-7

Dalian Join King Biochemical Tech. Co., Ltd.

Contact:0411 39216206

Address:814 First State Blvd
Shanghai Sungo Technology Chemical Co., Ltd

Contact:0086-21-51385579

Address:Room2010, F/20, Tonghua Plaza, NO 345 Jinxiang Road, Jinqiao Export Processing Zone, Shanghai, 201206 P.R.CHINA
Xi'an caijing Opto-Electrical Science & Technology Co., LTD

Contact:+86-29-88294447

Address:NO.168 Zhangba Rd. East, Xi'an, P.R.China
Suzhou Lixin Pharmaceutical Co., Ltd.

Contact:86-512-88169812

Address:21 Tangxi Road, Suzhou New District, Suzhou 215151
Beijing Chemdow Co., Ltd

website:http://www.chemdow.com

Contact:0086-10-82435335

Address:Room 401,Unit 3,4th Floor,Shangdijiayuan,Shangdi East Road, Haidian District,Beijing

Relevant to this article

C_(sp3)-H functionalization of methyl azaarenes: a calcium-catalyzed facile synthesis of (E)-2-styryl azaarenes and 2-aryl-1,3-bisazaarenes

Doi:10.1016/j.tetlet.2015.09.035
(2015)
Cu(0), O₂ and mechanical forces: a saving combination for efficient production of Cu-NHC complexes

Doi:10.1039/c6sc03182j
(2017)
An efficient synthesis of 2-(guaiazulen-1-yl)furan derivatives via intramolecular Wittig reactions

Doi:10.1016/j.cclet.2013.04.030
(2013)
Catalyst-Free and Solvent-Controlled Reductive Coupling of Activated Vinyl Triflates with Chlorotrimethylsilane by Magnesium Metal and Its Synthetic Application

Doi:10.1021/acs.orglett.8b00496
(2018)
2,6-Pyridinedicarboxylic acid as organocatalyst for the synthesis of 1,5-benzodiazepines through one-pot reaction

Doi:10.1016/j.tetlet.2013.05.148
(2013)
An environmentally benign synthesis of octahydro-2 H-chromen-4-ols via modified montmorillonite K10 catalyzed Prins cyclization reaction

Doi:10.1055/s-0032-1316915
(2013)

Article Doi