Synthesis of pyranoid analogues of the anti-HIV active 3'-deoxy-2',3'-didehydrothymidine (D4T)

Article abstract of DOI:10.1002/ardp.19923250808

The primary hydroxy group of ethyl 2,3-dideoxy-α-D-erythro-hex-2-enopyranoside (1) was selectively protected and the secondary hydroxy group was deoxygenated via the dithiiocarbonate 3 from which ethyl 6-O-(4-methoxybenzoyl)-2,3,4-trideoxy-α-D-glycero-hex