Asymmetric synthesis of a potent and selective competitive NMDA antagonist

DOI: 10.1021/jo00077a058

Source and publish data:

Journal of Organic Chemistry p. 7263 - 7270 (1993)

Update date:2022-08-04

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Authors:

Hamilton

Huang Huang

Yang Yang

Patch Patch

Narayanan

Ferkany Ferkany

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Article abstract of DOI:10.1021/jo00077a058

(2R,4R,5S)-2-Amino-4,5-(1,2-cyclohexyl)-7-phosphonoheptanoic acid (15) has been prepared by an efficient nine-step route (16% overall yield) which uses chemoenzymatic processes to establish all absolute stereochemistry. This compound was found to be the m

Full text of DOI:10.1021/jo00077a058

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