Tetrahedron Letters p. 5051 - 5054 (1992)
Update date:2022-07-29
Topics:
Duhamel, Lucette
Guillemont, Jerme
Poirier, Jean-Marie
Bromination of enamines of prenal and crotonaldehyde yields the corresponding ω-bromoaldehydes via the simple hydrolysis of iminium salts. The carbonyl function of these aldehydes can be protected as acetals or dioxolane. The overall process can be realized in a one pot procedure. The dioxolane is the starting material of a phosphonate which allows,by condensation with β-ionylidenacetaldehyde a direct access to the retinal with a 27.5% overall yield from the enamine 2.
website:http://www.tcfinechem.com/
Contact:18681346930
Address:baifu town,whou district
Jiangyin Tenghua Import&Export Co.,Ltd.
Contact:+86-510-86263875
Address:Room 402-B,9 Yanling Road, Jiangyin,Jiangsu, China
Shandong Loyal Chemical industrial Co.,Ltd
Contact:0533-7451788
Address:Linzi Chemical Industrial Park, Zibo, Shandong Province
Contact:+86-21-61318535
Address:Building 29,No.2139 Xizha Road, Fengxian District, Shanghai
Zhangjiagang Golden Reach Fine Chemical Co.,LTD.
Contact:+86-512-6585 6968
Address:Changfu Road， Dongsha Chemical Industry Park, Zhangjiagang City, Jiangsu Province, China
Doi:10.1021/ol401483j
(2013)Doi:10.1021/jo00052a001
(1992)Doi:10.1039/c3ob40445e
(2013)Doi:10.1039/c3ob40614h
(2013)Doi:10.1016/j.tet.2013.05.083
(2013)Doi:10.1002/chem.202003445
(2021)
