Tetrahedron Letters p. 5051 - 5054 (1992)
Update date:2022-07-29
Topics:
Duhamel, Lucette
Guillemont, Jerme
Poirier, Jean-Marie
Bromination of enamines of prenal and crotonaldehyde yields the corresponding ω-bromoaldehydes via the simple hydrolysis of iminium salts. The carbonyl function of these aldehydes can be protected as acetals or dioxolane. The overall process can be realized in a one pot procedure. The dioxolane is the starting material of a phosphonate which allows,by condensation with β-ionylidenacetaldehyde a direct access to the retinal with a 27.5% overall yield from the enamine 2.
Contact:+86-515-88356562
Address:No.2, West Daqing Road, Yancheng, Jiangsu, China
Contact:0833-5590788/5590338/5590055
Address:Victory in the town of Red Star Village,Mount Emei City,industrial concentration area storage processing logistics parkpark
Suzhou Ryan Pharmachem Technology Co.,Ltd
Contact:+86-0512-68780025
Address:B-301,No.2 Taishan Road,Suzhou New District,Jiangsu,P.R. China
Wuxi Pharma-Trading Import & Export Co.,Ltd.
Contact:+86-510-82304590 82716390
Address:Room 523,Youzu Alliance Building,No.88 Renmin Zhonglu,Wuxi,Jiangsu,China
Contact:+91 - 22 - 26355700
Address:17, Lotus Business Park, Andheri West
Doi:10.1021/ol401483j
(2013)Doi:10.1021/jo00052a001
(1992)Doi:10.1039/c3ob40445e
(2013)Doi:10.1039/c3ob40614h
(2013)Doi:10.1016/j.tet.2013.05.083
(2013)Doi:10.1002/chem.202003445
(2021)
