A new synthesis of C-nucleosides by 1,3-dipolar cycloaddition of chiral azomethine imines to methyl acrylate. The stereoselective synthesis of fused pyrazoles

Article abstract of DOI:10.1016/S0040-4020(01)80470-1

A new stereoselective synthesis of C-nucleosides is described. The fused NH,NH-dihydro pyrazole derivative 1 was transformed with carbohydrates into chiral azomethine imines 2-4. The 1,3-dipolar cycloaddition of these to methyl acrylate affords the nucleo