The squalestatins: Synthesis of C-4 carboxamide derivatives

DOI: 10.1016/S0040-4039(96)02049-7

Source and publish data:

Tetrahedron Letters p. 8925 - 8928 (1996)

Update date:2022-08-05

Topics:

Authors:

Chan, Chuen

Scicinski, Jan J.

Srikantha, Anton R. P.

Watson, Nigel S.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(96)02049-7

Synthesis of squalestatin S1 C-4 carboxamide, 2, as well as related C-4 amides and C-4 hydroxymethyl derivatives possessing a C-3 hydroxymethyl group (15 and 19) together with their SQS inhibitory activities are presented. Copyright (C) 1996 Elsevier Science Ltd.

Full text of DOI:10.1016/S0040-4039(96)02049-7

Products guided by the article

Product name:(1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-6-((E)-(4S,6S)-4,6-dimethyl-oct-2-enoyloxy)-4,7-dihydroxy-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid 4,5-di-tert-butyl ester

Cas No:144571-49-3

R&D Labs maybe for 144571-49-3

Jinan Xinke Pharmaceutical Science and Technology Co., Ltd.

Contact:+86 13256107535

Address:No. 592 the first gangxing road
PINGYUAN SIHUAN PHARMACEUTICAL CO., LTD

Contact:+86-531-55696072

Address:#2766,yinxiu Road, Economic Development Zone, Pingyuan Country, Shandong Province, China.
Wuhan Silworld Chemical Co.,Ltd

website:http://www.silworldchemical.com

Contact:+86-27-85613400

Address:No.198 jiangjun Road, Wuhan,China 430033
Jiangsu Dacheng Pharmaceutical and Chemical Co.,Ltd

Contact:+86-0517-87036900

Address:Chuzhou Chemical park, Huai'an, Jiangsu Province
NOVASYNCS CO., LTD

Contact:0512-63006287

Address:no.88.YISHENG Road,etdz-WUJIANG,SUZHOU,CHINA

Relevant to this article

Solvent-dependent switch of helical main-chain chirality in sergeants-and-soldiers-type poly(quinoxaline-2,3-diyl)s: Effect of the position and structures of the sergeant chiral units on the screw-sense induction

Doi:10.1021/ja403391m
(2013)
Discovery of 8-Methyl-pyrrolo[1,2-a]pyrazin-1(2 H)-one Derivatives as Highly Potent and Selective Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitors

Doi:10.1021/acs.jmedchem.9b01784
(2020)
The use of sodium chlorite in the direct synthesis of glycidic amides: Enantiopure synthesis of both enantiomers of norbalasubramide

Doi:10.1055/s-0032-1316893
(2013)
Cascade synthesis of azoquinazolinones by Cu(I)-catalyzed C-N coupling/C-H activation/C-N formation reactions under O₂

Doi:10.1016/j.tet.2013.05.071
(2013)
Reduction of 1,1-diaryl-substituted ethenes with sodium metal in dimethylformamide: A novel synthesis of α-hydroxybutanamides

Doi:10.1016/S0040-4039(00)61157-7
(1992)
Design, synthesis and structure-activity relationships of zwitterionic spirocyclic compounds as potent CCR1 antagonists

Doi:10.1016/j.bmcl.2013.05.087
(2013)

Article Doi