Reduction of 1,1-diaryl-substituted ethenes with sodium metal in dimethylformamide: A novel synthesis of α-hydroxybutanamides

DOI: 10.1016/S0040-4039(00)61157-7

Source and publish data:

Tetrahedron Letters p. 5601 - 5602 (1992)

Update date:2022-08-05

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Authors:

Botteghi

Gotta Gotta

Marchetti

Melloni Melloni

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Article abstract of DOI:10.1016/S0040-4039(00)61157-7

An unusual reactivity was observed in the reduction of 1,1-diphenylethene and 1-phenyl-1-(2-pyridyl)ethene with Na metal in DMF; the reaction afforded the corresponding N,N-dimethyl-4,4-diaryl-2-hydroxybutanamides in high yields.

Full text of DOI:10.1016/S0040-4039(00)61157-7

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