Synthesis of pyrido[2,3,4-kl]acridines a building block for the synthesis of pyridoacridine alkaloids

Article abstract of DOI:10.1016/S0040-4039(00)61150-4

Two new syntheses have been developed for the preparation of substituted pyrido[2,3,4-kl]acridines. The first synthesis involves a Skraup reaction and a nitrene insertion whereas the second includes a new pyridine ring synthesis starting from a 1-amino gr