Towards a Large Scale Preparation of Mexiprostil

DOI: 10.1016/S0040-4020(01)88229-6

Source and publish data:

Tetrahedron p. 6393 - 6402 (1992)

Update date:2022-08-03

Topics:

Authors:

Hijfte, L. Van

Kolb, M.

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Article abstract of DOI:10.1016/S0040-4020(01)88229-6

The enantioselective synthesis of mexiprostil (16R-16-methoxy-16-methyl PGE₁ methyl ester) is described.The assembly of the prostaglandin framework has been accomplished by the three component coupling process, via consecutive linking of the ω

Full text of DOI:10.1016/S0040-4020(01)88229-6

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