Synthesis of Carbocyclic Analogues of Guanosine 5'-(β-L-Fucopyranosyl diphosphate) (GDP-Fucose) as Potential Inhibitors of Fucosyltransferases

DOI: 10.1021/jo00051a004

Source and publish data:

Journal of Organic Chemistry p. 6693 - 6696 (1992)

Update date:2022-07-31

Topics:

Authors:

Cai, Shaopei

Stroud, Mark R.

Hakomori, Senitiroh

Toyokuni, Tatsushi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00051a004

Two carbocyclic analogues of GDP-fucose consisting of 5a-carba-β-L-fucopyranose and its unsaturated counterpart have been synthesized as potential inhibitors of fucosyltransferases through the intramolecular Emmons-Horner-Wadsworth olefination of the 2,6-

Full text of DOI:10.1021/jo00051a004

Products guided by the article

Product name:((2S,3S,4R,5R,6S)-3,4,5-Tris-benzyloxy-2-hydroxy-6-methyl-tetrahydro-pyran-2-ylmethyl)-phosphonic acid dimethyl ester

Cas No:144668-22-4

R&D Labs maybe for 144668-22-4

Jinan Jinguilin Chemical Co.,Ltd

Contact:+86-531-81188412

Address:3rd floor of Torch Building, Huanyuan Rd, City of Jinan
Shanghai Massive Chemical Technology Co., Ltd.

website:http://www.massivechem.com/

Contact:+86 21 34943721

Address:Room 435, 4th floor, Building 9, No. 2568 Gudai Road,Minhang District, Shanghai,
Beijing Century Richap Chemistry Co.,Ltd

Contact:+86- 010-64455497

Address:Guannan County, Lianyungang City, Jiangsu Province, China
Puyang Willing Chemicals Co.,Ltd.

Contact:86-393-4840366

Address:Puyang Henan China
SHANGHAI ARCADIA BIOTECHNOLOGY LTD.

Contact:+86-21-61353236

Address:SUITE 901, BUILDING WENSLI, 1378 LU JIA BANG RD, SHANGAHI 200011, P.R.CHINA

Relevant to this article

Novel Free Radical Ring-Forming Reaction of Dichlorocyclobutanones and Sequential Ring Expansion

Doi:10.1021/ja00051a064
(1992)
One-pot synthesis of (guaiazulen-1-yl)furan derivatives from guaiazulene and 1,4-diaryl-2-butene-1,4-diones

Doi:10.3987/COM-13-12690
(2013)
Rhodium-Catalyzed Direct C-H Bond Cyanation in Ionic Liquids

Doi:10.1021/acs.orglett.8b01952
(2018)
Design, synthesis, and cytotoxicity of pyridine, pyrazole, and thiazole derivatives derived from N-alkyl-4,5,6,7-tetrahydro-1-benzothiophene

Doi:10.1007/s10593-013-1259-4
(2013)
Structure and thermotropic phase behavior of a homologous series of bioactive N-acyldopamines

Doi:10.1021/jp402750m
(2013)
Chemoselective oxidative hydrolysis of EWG protected α-arylamino vinyl bromides to α-arylamino-α′-bromoacetones

Doi:10.1016/j.tetlet.2013.05.118
(2013)

Article Doi