Michael-Michael ring closure reaction of benzyl cyanides and chalcones

DOI: 10.1055/s-1992-26289

Source and publish data:

Synthesis p. 1003 - 1006 (1992)

Update date:2022-08-05

Topics:

Authors:

Al-Arab Al-Arab

Ghanem Ghanem

Olmstead

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Article abstract of DOI:10.1055/s-1992-26289

The synthesis of a number of highly substituted cyclohexane derivatives has been accomplished in a single step reaction of benzyl cyanides and chalcones (1:2) using sodium ethoxide in anhydrous diethyl ether at room temperature to give 3-aroyl-1,2,4,6-tet

Full text of DOI:10.1055/s-1992-26289

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Product name:(1R*,2R*,3S*,4S*,6S*)-(+/-)-2,6-Bis-(4-methoxyphenyl)-1-(3,4-dichlorophenyl)-4-hydroxy-3-(2-naphthoyl)-4-(2-naphthyl)cyclohexanecarbonitrile

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