Enantioselective conjugate addition of 3-fluoro-oxindoles to vinyl sulfone: An organocatalytic access to chiral 3-fluoro-3-substituted oxindoles

DOI: 10.1039/c3ob41267a

Source and publish data:

Organic and Biomolecular Chemistry p. 5217 - 5221 (2013)

Update date:2022-09-26

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Authors:

Dou, Xiaowei

Lu, Yixin

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Article abstract of DOI:10.1039/c3ob41267a

An organocatalytic conjugate addition of prochiral 3-fluorinated oxindoles to vinyl sulfones was described for the first time. In the presence of bifunctional tertiary amine-thiourea catalysts, 3-fluoro-3-substituted oxindole adducts were obtained in exce

Full text of DOI:10.1039/c3ob41267a

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