Tetrahedron p. 7879 - 7886 (1992)
Update date:2022-08-03
Topics:
Butler
George
The nonenzymatic cyclic dimerisation of 5-aminolevulinic aid (5-ALA) leads to the formation of a pyrazine (3) and, under some circumstances, pseudo-porphobilinogen (1). On the other hand, the enzyme-catalysed process leads to porphobilinogen (PBG). The products of the former reaction were identified from their NMR spectra and mechanisms for their formation are proposed.
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Doi:10.1021/ol401642n
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(2012)Doi:10.1021/jo401325t
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(2013)Doi:10.1039/c8ob01075g
(2018)Doi:10.1248/cpb.30.3912
(1982)
