Regioselective Nucleophilic Attack on N-BOC-Pyroglutamate Ethyl Ester

DOI: 10.1016/S0040-4039(00)61153-X

Source and publish data:

Tetrahedron Letters p. 5589 - 5590 (1992)

Update date:2022-07-29

Topics:

Authors:

Ezquerra, Jesus

Mendoza, Javier de

Pedregal, Concepcion

Ramirez, Carmen

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)61153-X

N-BOC ethyl pyroglutamate undergoes regioselective ring opening with different nucleophiles without racemization at the chiral centre.Key words: Pyroglutamate, Amino Acid, Asymmetric Synthesis

Full text of DOI:10.1016/S0040-4039(00)61153-X

Products guided by the article

Product name:(Z)-(S)-2-tert-Butoxycarbonylamino-7-hydroxy-7-(3-methoxy-phenyl)-5-oxo-hept-6-enoic acid ethyl ester

Cas No:144978-14-3

R&D Labs maybe for 144978-14-3

Xi'an Terra Biochem Co. Ltd.

Contact:0086-29-88315623

Address:S711, Innovation Bldg No.25 Gaoxin 1st Rd, Xian P.R of China 710075
Innua Petrochem Ltd.

Contact:+1-284-4950244

Address:Box 3069, Road Town, Tortola, British Virgin Islands
Beijing Merson Pharmaceutical Co., Ltd

Contact:0086-10-80484934 0086-10-80484574/

Address:2nd Floor , No. 2 Building , No. 14 Houshayu Duan, Jingmi Road ,Shunyi District , Beijing 101318, P.R.China
Nanjing Legend Pharmaceutical & Chemical Co., Ltd.

Contact:+86-25-83767696

Address:14-7 Zhongshan Lu Guluo District, Nanjing
SHANGHAI ARCADIA BIOTECHNOLOGY LTD.

Contact:+86-21-61353236

Address:SUITE 901, BUILDING WENSLI, 1378 LU JIA BANG RD, SHANGAHI 200011, P.R.CHINA

Relevant to this article

Silicon(II) coordination chemistry: N-heterocyclic carbene complexes of Si²⁺ and SiI⁺

Doi:10.1002/anie.201301363
(2013)
Solution phase structures of enantiopure and racemic lithium N-benzyl-N-(α-methylbenzyl)amide in THF: Low temperature ⁶Li and ¹⁵N NMR spectroscopic studies

Doi:10.1016/j.tetasy.2013.07.001
(2013)
Kinetically Controlled Peptide Bond Formation in Anhydrous Alcohol Catalyzed by the Industrial Protease Alcalase

Doi:10.1021/jo00051a052
(1992)
A fundamental relationship between hydrophobic properties and biological activity for the duocarmycin class of DNA-alkylating antitumor drugs: Hydrophobic-binding-driven bonding

Doi:10.1021/jm400665c
(2013)
Efficient sialylation with phosphite as leaving group

Doi:10.1016/S0040-4039(00)60022-9
(1992)
Photolysis of 1,3-dimesitylhexamethyltrisilane and 1,2-dimesityltetramethyldisilane

Doi:10.1021/om00025a034
(1993)

Article Doi