Synthesis and antiarrhythmic activity of 2,2-dialkyl-1'-(N-substituted aminoalkyl)-spiro-[chroman-4,4'-imidazolidine]-2',5'-diones

DOI: 10.1248/cpb.40.1823

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1823 - 1827 (1992)

Update date:2022-08-03

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Authors:

Matsukura

Daiku Daiku

Ueda Ueda

Tanaka Tanaka

Igarashi

Minami Minami

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Article abstract of DOI:10.1248/cpb.40.1823

A novel series of 2,2-dialkyl-1'-(N-substituted aminoalkyl)-spiro-[chroman-4,4'-imidazolidine]-2',5'-diones was synthesized and evaluated for antiarrhythmic activity in chloroform- or/and aconitine-induced ventricular arrhythmia in mice. Among these compo

Full text of DOI:10.1248/cpb.40.1823

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