
Tetrahedron p. 16287 - 16298 (1997)
Update date:2022-08-03
Topics: Total synthesis Stereoselective D-Glucose
Chida, Noritaka
Takeoka, Jun
Ando, Kohji
Tsutsumi, Noriko
Ogawa, Seiichiro
The chiral and stereoselective synthesis of (+)-lactacystin 1, the first non-protein neurotrophic factor having an α,α-disubstituted α- amino acid structure, is described. The highly functionalized γ- lactam portion possessing a tetra-substituted carbon w
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(1967)