Dilithiation of 2-(Chloromethyl)-3-tosylpropene: Synthesis and Reactivity of a New Chlorinated Allyl Sulfone Dianion

DOI: 10.1016/S0040-4039(00)79038-1

Source and publish data:

Tetrahedron Letters p. 6543 - 6546 (1992)

Update date:2022-08-03

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Authors:

Najera, Carmen

Sansano, Jose M.

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Article abstract of DOI:10.1016/S0040-4039(00)79038-1

Double lithiation of 2-(chloromethyl)3-tosylpropene (4) with n-butyl-lithium at -90 deg C in the presence of DMPU leads to the dianion 5, which by reaction with deuterium oxide affords the corresponding 3,3-dideuteriated product 6.The alkylation reaction

Full text of DOI:10.1016/S0040-4039(00)79038-1

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