Tetrahedron Letters p. 6543 - 6546 (1992)
Update date:2022-08-03
Topics:
Najera, Carmen
Sansano, Jose M.
Double lithiation of 2-(chloromethyl)3-tosylpropene (4) with n-butyl-lithium at -90 deg C in the presence of DMPU leads to the dianion 5, which by reaction with deuterium oxide affords the corresponding 3,3-dideuteriated product 6.The alkylation reaction
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Doi:10.1021/ja00437a085
(1976)Doi:10.1134/S1070428013080241
(2013)Doi:10.1039/DT9920003337
(1992)Doi:10.1002/cjoc.201300365
(2013)Doi:10.1016/S0040-4039(00)61773-2
(1992)Doi:10.1039/c3ob41247d
(2013)
