Tetrahydropyran Derivatives from γ- and δ-Hexonolactones

Article abstract of DOI:10.1016/S0040-4039(00)76908-5

Both δ- and γ-hexonolactones provide templates for the construction of bicyclic lactones in which a new tetrahydropyran ring has been formed from overall elimination of water from the C-2 and C-6 hydroxyl groups.Such studies may provide a strategy for the syntheis of C-glycosides from elimination of water between C-2 and C-6 of heptonolactones.